Stringent requirement for spatial arrangement of extracellular matrix in supporting cell morphogenesis and differentiation
نویسندگان
چکیده
منابع مشابه
Extracellular matrix elasticity directs stem cell differentiation.
Stem cell differentiation is regulated by a variety of cues including growth factors and extracellular matrix (ECM), although the role that the ECM has in this process is less understood. Here we provide examples of how the composition, concentration, and elastic modulus of matrix as well as its temporal and spatial location plays a key role in regulating cell fate. Natural variation of matrix ...
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ژورنال
عنوان ژورنال: BMC Cell Biology
سال: 2014
ISSN: 1471-2121
DOI: 10.1186/1471-2121-15-10